Research Efforts

  • NCI-NIH Funded clinical study: Current patients and others interested in our research have asked about the status of the NCI-NIH funded clinical study of our work. Click here for more information.
  • History of Enzyme Therapy: This section describes Dr. Gonzalez's investigations into enzyme therapy and cancer treatment, starting in 1981 with his investigation into the work of Dr. William Donald Kelley.
  • The Nutritional Research and Educational Foundation, Inc: The Foundation was established in 1994 to administer the grant for the pancreatic cancer pilot study (see below). It fosters research in the areas of nutrition and cancer, and hopes to sponsor more animal studies if sufficient funds become available.
  • Alternative Therapies in Health and Medicine: This peer-reviewed healthcare journal is indexed in the National Library of Medicine. It serves as a forum for research evidence and information concerning the practical use of alternative therapies. The January/February 2007 issue featured a lengthy interview with Dr. Gonzalez as well as an article by Dr. Gonzalez and Dr. Isaacs which includes several case reports of cancer patients successfully treated with enzyme therapy. The March/April 2007 issue included an article by Dr. Isaacs about evaluating anecdotal evidence and case reports.
  • 2004 Pancreatic Cancer Animal Study: The abstract from the article that appeared in the peer-reviewed journal Pancreas. This report details the results of the administration of the pancreatic enzyme material used by Dr. Gonzalez and Dr. Isaacs in their treatment protocols to a group of mice with experimentally induced pancreatic cancer. This study in animals did not perfectly reproduce the program as it is administered to humans, but nonetheless the results were very positive.
  • 1999 Pancreatic Cancer Pilot Study: The abstract from the article by Dr. Gonzalez and Dr. Isaacs that appeared in the peer-reviewed journal Nutrition and Cancer. This report details the results of their first clinical trial, a pilot study, in pancreatic cancer.
  • 1993 Best Case Series: The presentation of “best cases” is a tool that was devised by the National Cancer Institute for the evaluation of possible new cancer therapies. Dr. Gonzalez made his presentation of “best cases” to the National Cancer Institute in 1993, and subsequently presented three of them at a National Institutes of Health Workshop on Alternative Medicine in June of 1994. A summary of Dr. Gonzalez’s presentation appeared in an NIH newsletter.
  • Discoveries in Medicine Article: This article from the fall of 1990 details some of Dr. Gonzalez's early research efforts into enzyme therapy and the work of Dr. William Donald Kelley.

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Nicholas J. Gonzalez, MD PC
Linda L. Isaacs, MD
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